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Ivo S F Melo Selected Research

2-phthalimidethanol

8/20172-Phthalimidethanol and 2-phthalimidethyl nitrate inhibit mechanical allodynia, neutrophil recruitment and cytokine and chemokine production in a murine model of articular inflammation.
6/2015Activities of 2-phthalimidethyl nitrate and 2-phthalimidethanol in the models of nociceptive response and edema induced by formaldehyde in mice and preliminary investigation of the underlying mechanisms.
7/2014Activities of 2-phthalimidethanol and 2-phthalimidethyl nitrate, phthalimide analogs devoid of the glutarimide moiety, in experimental models of inflammatory pain and edema.

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Ivo S F Melo Research Topics

Disease

14Hyperalgesia
12/2023 - 07/2014
13Pain (Aches)
09/2023 - 06/2014
11Inflammation (Inflammations)
09/2023 - 06/2014
10Edema (Dropsy)
09/2023 - 06/2014
7Neuralgia (Stump Neuralgia)
12/2023 - 01/2018
4Nociceptive Pain
02/2020 - 06/2014
2Type 2 Diabetes Mellitus (MODY)
02/2022 - 09/2019
2Pleurisy (Pleuritis)
02/2022 - 12/2015
1Pathologic Processes
01/2023
1Septic Shock (Toxic Shock Syndrome)
04/2020
1Sepsis (Septicemia)
04/2020
1Hypersensitivity (Allergy)
04/2020
1Pneumonia (Pneumonitis)
04/2020
1Infections
04/2020
1Rheumatoid Arthritis
01/2018

Drug/Important Bio-Agent (IBA)

10CarrageenanIBA
01/2023 - 06/2014
5Paclitaxel (Taxol)FDA LinkGeneric
12/2023 - 01/2018
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2023 - 01/2018
5Naltrexone (ReVia)FDA LinkGeneric
02/2020 - 06/2014
4phthalimideIBA
01/2023 - 07/2014
3CytokinesIBA
12/2023 - 08/2017
3Metformin (Glucophage)FDA LinkGeneric
12/2023 - 09/2019
3Formaldehyde (Formol)FDA Link
12/2019 - 06/2015
3Nicorandil (SG 75)IBA
04/2018 - 12/2015
32-phthalimidethyl nitrateIBA
08/2017 - 07/2014
32-phthalimidethanolIBA
08/2017 - 07/2014
3hydroxide ionIBA
08/2017 - 07/2014
3Opioid Analgesics (Opioids)IBA
12/2015 - 06/2014
2ZymosanIBA
09/2023 - 06/2014
2Clindamycin (Cleocin)FDA LinkGeneric
09/2023 - 04/2020
2LipopolysaccharidesIBA
09/2023 - 01/2023
2Hydrogen Sulfide (Sulfide, Hydrogen)IBA
01/2023 - 08/2019
2Analgesics (Analgesic Drugs)IBA
01/2023 - 12/2015
2Hypoglycemic Agents (Hypoglycemics)IBA
02/2022 - 09/2019
2Niacinamide (Nicotinamide)FDA LinkGeneric
02/2020 - 12/2015
2Vitamin B Complex (B Vitamins)IBA
02/2020 - 10/2017
2Thiamine (Aneurin)FDA Link
02/2020 - 10/2017
2Riboflavin (Vitamin B2)FDA LinkGeneric
02/2020 - 10/2017
2Freund's AdjuvantIBA
12/2019 - 10/2017
2glutarimideIBA
12/2019 - 07/2014
2Glyburide (Glibenclamide)FDA LinkGeneric
09/2019 - 04/2018
2Cyproheptadine (Periactin)FDA Link
04/2018 - 06/2014
2Narcotic Antagonists (Opioid Antagonists)IBA
12/2015 - 06/2014
1ThionesIBA
01/2023
1IsoindolesIBA
01/2023
1GasotransmittersIBA
01/2023
1CurcuminIBA
04/2022
1Potassium Channels (Potassium Channel)IBA
02/2022
1Adenosine Triphosphate (ATP)IBA
02/2022
1KATP ChannelsIBA
02/2020
1Therapeutic UsesIBA
09/2019
1AMP-Activated Protein KinasesIBA
09/2019
14-methylbenzenecarbothioamideIBA
08/2019
1Leflunomide (Arava)FDA LinkGeneric
01/2018
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2017
1Dexamethasone (Maxidex)FDA LinkGeneric
10/2017
1AntigensIBA
08/2017
1methylated bovine serum albumin (MBSA)IBA
08/2017
1ChemokinesIBA
08/2017
1CannabinoidsIBA
06/2015
1Thalidomide (Thalomid)FDA Link
07/2014
1azadirachtin (azadirachtin A)IBA
06/2014

Therapy/Procedure

3Injections
12/2023 - 10/2017
2Intra-Articular Injections
09/2023 - 08/2017